Research

Bacteriology in uncomplicated urinary tract infections in Norwegian general practice from 2001–2015

Marianne Bollestad, Ingvild Vik, Nils Grude, Hege Salvesen Blix, Hanne Brekke and Morten Lindbaek
BJGP Open 2018; 1 (4): bjgpopen17X101145. DOI: https://doi.org/10.3399/bjgpopen17X101145

Article Figures & Data

Figures

  • Figure 1
    Figure 1 Total use of selected antibiotics commonly used to treat urinary tract infections in Norway (wholesale statistics).aIn 2000-2002, nalidixic acid and sulfathiazole were also used in Norway, however these two represented less than 0.3% of total use of antibiotics with the indication urinary tract. 
  • Figure 2
    Figure 2 Distribution of use measured as number of prescriptions for selected antibiotics per 1000 women and men >20 years of age.
  • Figure 3
    Figure 3 Total use of trimethoprim (wholesale statistics) and prevalence of resistant strains of E.coli isolates in urinary tract isolates from the national register (NORM) and the three different general practice cohorts.
  • Figure 4
    Figure 4 Total use of pivmecillinam and mecillinam (wholesale statistics) and prevalence of resistant strains of E.coli isolates in urinary tract isolates from the national register (NORM) and the three different general practice cohorts.

Tables

  • Table 1. Bacterial isolates from the three study cohorts
    Microbe2001 n (%)2010–2011 n (%)2013–2015 n (%)
    E. coli 112 (82.4)a 180 (78.3)a 129 (81.6)a
    Staph. saprophyticus 8 (5.9)a 38 (16.5)a 22 (13.9)a
    Enterobacter spp.0a 1 (0.4)a 4 (2.5)a
    Enterococcus faecalis 3 (2.2)a 2 (0.9)a 1 (0.6)a
    Klebsiella spp. 6 (4.4)a 5 (2.2)a 2 (1.3)a
    Proteus spp. 5 (3.7)a 4 (1.7)a 0a
    Staph. aureus 2 (1.5)a 0a 0a
    No significant growth48 (26.1)b 176 (43.3)b 101 (39.0)b
    Total number of cultures with significant bacteriuria136 (73.9)b 230 (56.7)b 158 (61.0)°b
    Total number of cultures184406259

    • a% of total number of cultures with significant bacteriuria. b% of total number of cultures.

  • Table 2. Resistance to antibiotics commonly used to treat UTIs
    MicrobeAntibiotic2001 n (%) [95 % CI] 2010–2011 n (%) [95 % CI]2013–2015 n (%) [95 % CI]
    E. coli Mecillinam7 (6.3) [1.8 to 10.8]4 (2.2) [0.1 to 4.3]11 (8.5) [3.7 to 13.3]
    Nitrofurantoin3 (2.7) [0.0 to 5.7]00
    Trimethoprim13 (11.6) [5.7 to 17.5]38 (21.1) [15.1 to 27.1]27 (20.9) [13.9 to 27.9]
    Co-trimoxazoleNA39 (21.7) [15.7 to 27.7]24 (18.6) [11.9 to 25.3]
    Sulphonamide21 (18.8) [11.6 to 26.0]NANA
    Amoxicillin31 (27.7) [19.4 to 36.0]63 (35.0) [28.0 to 42.0]38 (29.5) [21.6 to 37.4]
    CiprofloxacinNANANA
    Staph. saprophyticus MecillinamNANANA
    Nitrofurantoin000
    Trimethoprim001 (4.5) [–4.2 to 13.2]
    Co-trimoxazoleNA00
    Sulphonamide0NANA
    AmoxicillinNA4 (10.5) [0.8 to 20.2]4 (18.2) [2.1 to 34.3]
    CiprofloxacinNANANA

    • NA = not applicable, isolate was not tested for this antibiotic.

Back to top

In this issue

BJGP Open
Vol. 1, Issue 4
January 2018
Download PDF
Download PowerPoint
Email Article
Citation Tools
Bacteriology in uncomplicated urinary tract infections in Norwegian general practice from 2001–2015
Marianne Bollestad, Ingvild Vik, Nils Grude, Hege Salvesen Blix, Hanne Brekke, Morten Lindbaek
BJGP Open 2018; 1 (4): bjgpopen17X101145. DOI: 10.3399/bjgpopen17X101145
del.icio.us logo Facebook logo Mendeley logo Bluesky logo

Jump to section

Keywords

Intended for Healthcare Professionals
 
 

British Journal of General Practice