The stress system in the human brain in depression and neurodegeneration
DF Swaab, AM Bao, PJ Lucassen - Ageing research reviews, 2005 - Elsevier
Corticotropin-releasing hormone (CRH) plays a central role in the regulation of the
hypothalamic-pituitary-adrenal (HPA)-axis, ie, the final common pathway in the stress response. The …
hypothalamic-pituitary-adrenal (HPA)-axis, ie, the final common pathway in the stress response. The …
α-Glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis
FA Van de Laar, PL Lucassen, RP Akkermans… - Diabetes …, 2005 - Am Diabetes Assoc
OBJECTIVE—To review the effects of monotherapy with α-glucosidase inhibitors (AGIs) for
patients with type 2 diabetes, with respect to mortality, morbidity, glycemic control, insulin …
patients with type 2 diabetes, with respect to mortality, morbidity, glycemic control, insulin …
Which drugs cause preventable admissions to hospital? A systematic review
…, S Royal, G Pipe, P Lucassen… - British journal of …, 2007 - Wiley Online Library
Aims Previous systematic reviews have found that drug‐related morbidity accounts for 4.3%
of preventable hospital admissions. None, however, has identified the drugs most commonly …
of preventable hospital admissions. None, however, has identified the drugs most commonly …
[PDF][PDF] Human adult neurogenesis: evidence and remaining questions
Renewed discussion about whether or not adult neurogenesis exists in the human
hippocampus, and the nature and strength of the supporting evidence, has been reignited by two …
hippocampus, and the nature and strength of the supporting evidence, has been reignited by two …
Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action
Adult hippocampal neurogenesis, a once unorthodox concept, has changed into one of the
most rapidly growing fields in neuroscience. The present report results from the ECNP …
most rapidly growing fields in neuroscience. The present report results from the ECNP …
Post-acute and long-COVID-19 symptoms in patients with mild diseases: a systematic review
…, TC Olde Hartman, PLBJ Lucassen… - Family …, 2022 - academic.oup.com
Background It is expected that GPs are increasingly confronted with a large group of patients
with symptoms persisting three weeks after initial symptoms of a mild (managed in the …
with symptoms persisting three weeks after initial symptoms of a mild (managed in the …
[HTML][HTML] Neuropathology of stress
Environmental challenges are part of daily life for any individual. In fact, stress appears to be
increasingly present in our modern, and demanding, industrialized society. Virtually every …
increasingly present in our modern, and demanding, industrialized society. Virtually every …
What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated?
B Czéh, PJ Lucassen - European archives of psychiatry and clinical …, 2007 - Springer
Even though in vivo imaging studies document significant reductions of hippocampal
volume in depressed patients, the exact underlying cellular mechanisms are unclear. Since …
volume in depressed patients, the exact underlying cellular mechanisms are unclear. Since …
[PDF][PDF] Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression
FC Raadsheer, JJ Heerikhuize, PJ Lucassen… - American Journal of …, 1995 - pure.knaw.nl
… A modification of the method of Lucassen et al. (30) was used for the in situ hybridization …
Hybridization conditions were the same as those described by Lucassen et al. (30), except for …
Hybridization conditions were the same as those described by Lucassen et al. (30), except for …
[HTML][HTML] The indispensable roles of microglia and astrocytes during brain development
K Reemst, SC Noctor, PJ Lucassen… - Frontiers in human …, 2016 - frontiersin.org
Glia are essential for brain functioning during development and in the adult brain. Here, we
discuss the various roles of both microglia and astrocytes, and their interactions during brain …
discuss the various roles of both microglia and astrocytes, and their interactions during brain …