User profiles for O. E. Okosieme

Onyebuchi Okosieme

Honorary Professor, Cardiff University
Verified email at Cardiff.ac.uk
Cited by 5135

Global epidemiology of hyperthyroidism and hypothyroidism

…, JH Lazarus, CM Dayan, OE Okosieme - Nature Reviews …, 2018 - nature.com
Thyroid hormones are essential for growth, neuronal development, reproduction and regulation
of energy metabolism. Hypothyroidism and hyperthyroidism are common conditions with …

Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies

…, R Peter, OE Okosieme - International journal of …, 2010 - Wiley Online Library
Background: Patients with diabetes mellitus are at an increased risk of thyroid disease. The
frequency of thyroid dysfunction in diabetic patients is higher than that of the general …

Therapy of endocrine disease: impact of iodine supplementation in mild-to-moderate iodine deficiency: systematic review and meta-analysis

PN Taylor, OE Okosieme, CM Dayan… - European Journal of …, 2014 - academic.oup.com
… Study selection and data extraction were independently conducted by two reviewers (PN
Taylor and OE Okosieme) using preset selection criteria. Differences were resolved by …

TSH levels and risk of miscarriage in women on long-term levothyroxine: a community-based study

…, S Thomas, CM Dayan, OE Okosieme - The Journal of …, 2014 - academic.oup.com
Context: Thyroid dysfunction is associated with adverse obstetric outcomes, but there is
limited information on pregnancy outcomes in women established on levothyroxine. Objective: …

Primary therapy of Graves' disease and cardiovascular morbidity and mortality: a linked-record cohort study

OE Okosieme, PN Taylor, C Evans… - The lancet Diabetes & …, 2019 - thelancet.com
Background Graves' disease is routinely treated with antithyroid drugs, radioiodine, or surgery,
but whether the choice of initial therapy influences long-term outcomes is uncertain. We …

Adequacy of thyroid hormone replacement in a general population

OE Okosieme, G Belludi, K Spittle… - … Journal of Medicine, 2011 - academic.oup.com
Background: Suboptimal thyroid hormone replacement may carry harmful health consequences.
Aims: Our objectives were to determine the prevalence and factors associated with …

Maternal perchlorate levels in women with borderline thyroid function during pregnancy and the cognitive development of their offspring: data from the Controlled …

PN Taylor, OE Okosieme, R Murphy… - The Journal of …, 2014 - academic.oup.com
Objective: Thyroid dysfunction is associated with impaired cognitive development. Perchlorate
decreases thyroidal iodine uptake, potentially reducing thyroid hormone production. It is …

Thyroxine replacement: a clinical endocrinologist's viewpoint

V Eligar, PN Taylor, OE Okosieme… - Annals of clinical …, 2016 - journals.sagepub.com
Background Hypothyroidism affects 2–5% of the general population. Patients with uncorrected
disease suffer significant morbidity and have an increased risk of cardiovascular disease …

Thyroglobulin antibodies in serum of patients with differentiated thyroid cancer: relationship between epitope specificities and thyroglobulin recovery

OE Okosieme, C Evans, L Moss, AB Parkes… - Clinical …, 2005 - academic.oup.com
Background: Serum antibodies against thyroglobulin (TgAbs) are common in patients with
differentiated thyroid cancer (DTC) and can interfere in thyroglobulin (Tg) assays. We …

Preconception management of thyroid dysfunction

OE Okosieme, I Khan, PN Taylor - Clinical endocrinology, 2018 - Wiley Online Library
Uncorrected thyroid dysfunction in pregnancy has well‐recognized deleterious effects on
foetal and maternal health. The early gestation period is one of the critical foetal vulnerability …