Growth factors in the treatment of diabetic foot ulcers
…, GD Griffiths, AM Schor, GP Leese… - Journal of British …, 2003 - academic.oup.com
… either topical PDGF 30 µg per g gel or placebo daily. After 20 … g gel daily had no effect on
ulcer healing (36 per cent healed with PDGF, 35 per cent with placebo) but PDGF 100 µg per g …
ulcer healing (36 per cent healed with PDGF, 35 per cent with placebo) but PDGF 100 µg per g …
Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee
The management of primary hypothyroidism with levothyroxine (L‐T4) is simple, effective
and safe, and most patients report improved well‐being on initiation of treatment. However, a …
and safe, and most patients report improved well‐being on initiation of treatment. However, a …
[HTML][HTML] Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus: systematic review of observational studies
Background Glycaemic control in women with diabetes is critical to satisfactory pregnancy
outcome. A systematic review of two randomised trials concluded that there was no clear …
outcome. A systematic review of two randomised trials concluded that there was no clear …
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
D Cuthbertson, K Smith, J Babraj, G Leese… - The FASEB …, 2005 - Wiley Online Library
… g of EAA, concentrations of leucine fell from basal, and at 5 g… At higher doses (ie, 10–20 g),
intramuscular leucine rose to … ingestion of 2.5 g of EAA but at the higher doses (10–40 g), the …
intramuscular leucine rose to … ingestion of 2.5 g of EAA but at the higher doses (10–40 g), the …
Frequency and predictors of hypoglycaemia in Type 1 and insulin‐treated Type 2 diabetes: a population‐based study
…, R Durrant, MM Band, G Reekie, GP Leese - Diabetic …, 2005 - Wiley Online Library
Aims To ascertain the frequency and identify predictors of self‐reported hypoglycaemia in
Type 1 and insulin‐treated Type 2 diabetes. Methods A random sample of 267 people with …
Type 1 and insulin‐treated Type 2 diabetes. Methods A random sample of 267 people with …
The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients …
…, N Peden, A Jamieson, D Matthews, G Leese… - Bmj, 2008 - bmj.com
Objective To determine whether aspirin and antioxidant therapy, combined or alone, are
more effective than placebo in reducing the development of cardiovascular events in patients …
more effective than placebo in reducing the development of cardiovascular events in patients …
Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use
GP Leese, J Wang, J Broomhall, P Kelly… - Diabetes …, 2003 - Am Diabetes Assoc
OBJECTIVE—To determine the incidence, predisposing factors, and costs of emergency
treatment of severe hypoglycemia in people with type 1 and type 2 diabetes. RESEARCH …
treatment of severe hypoglycemia in people with type 1 and type 2 diabetes. RESEARCH …
Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010
Importance Type 1 diabetes has historically been associated with a significant reduction in
life expectancy. Major advances in treatment of type 1 diabetes have occurred in the past 3 …
life expectancy. Major advances in treatment of type 1 diabetes have occurred in the past 3 …
Barriers to physical activity in patients with diabetes
N Thomas, E Alder, GP Leese - Postgraduate medical journal, 2004 - academic.oup.com
Purpose Two questions were addressed: (1) How much physical activity do patients with
diabetes perform? (2) What are the perceived factors that prevent patients from doing more …
diabetes perform? (2) What are the perceived factors that prevent patients from doing more …
Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy
…, TM MacDonald, AD Morris, GP Leese - The Journal of …, 2010 - academic.oup.com
Context: For patients on T 4 replacement, the dose is guided by serum TSH concentrations,
but some patients request higher doses due to adverse symptoms. Objective: The aim of the …
but some patients request higher doses due to adverse symptoms. Objective: The aim of the …