Growth factors in the treatment of diabetic foot ulcers

…, GD Griffiths, AM Schor, GP Leese… - Journal of British …, 2003 - academic.oup.com
… either topical PDGF 30 µg per g gel or placebo daily. After 20 … g gel daily had no effect on
ulcer healing (36 per cent healed with PDGF, 35 per cent with placebo) but PDGF 100 µg per g

Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

…, K Boelaert, C Dayan, M Gurnell, G Leese… - Clinical …, 2016 - Wiley Online Library
The management of primary hypothyroidism with levothyroxine (L‐T4) is simple, effective
and safe, and most patients report improved well‐being on initiation of treatment. However, a …

[HTML][HTML] Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus: systematic review of observational studies

ME Inkster, TP Fahey, PT Donnan, GP Leese… - BMC pregnancy and …, 2006 - Springer
Background Glycaemic control in women with diabetes is critical to satisfactory pregnancy
outcome. A systematic review of two randomised trials concluded that there was no clear …

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

D Cuthbertson, K Smith, J Babraj, G Leese… - The FASEB …, 2005 - Wiley Online Library
g of EAA, concentrations of leucine fell from basal, and at 5 g… At higher doses (ie, 10–20 g),
intramuscular leucine rose to … ingestion of 2.5 g of EAA but at the higher doses (10–40 g), the …

Frequency and predictors of hypoglycaemia in Type 1 and insulin‐treated Type 2 diabetes: a population‐based study

…, R Durrant, MM Band, G Reekie, GP Leese - Diabetic …, 2005 - Wiley Online Library
Aims To ascertain the frequency and identify predictors of self‐reported hypoglycaemia in
Type 1 and insulin‐treated Type 2 diabetes. Methods A random sample of 267 people with …

The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients …

…, N Peden, A Jamieson, D Matthews, G Leese… - Bmj, 2008 - bmj.com
Objective To determine whether aspirin and antioxidant therapy, combined or alone, are
more effective than placebo in reducing the development of cardiovascular events in patients …

Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use

GP Leese, J Wang, J Broomhall, P Kelly… - Diabetes …, 2003 - Am Diabetes Assoc
OBJECTIVE—To determine the incidence, predisposing factors, and costs of emergency
treatment of severe hypoglycemia in people with type 1 and type 2 diabetes. RESEARCH …

Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010

…, HC Looker, RS Lindsay, SH Wild, N Joss, G Leese… - Jama, 2015 - jamanetwork.com
Importance Type 1 diabetes has historically been associated with a significant reduction in
life expectancy. Major advances in treatment of type 1 diabetes have occurred in the past 3 …

Barriers to physical activity in patients with diabetes

N Thomas, E Alder, GP Leese - Postgraduate medical journal, 2004 - academic.oup.com
Purpose Two questions were addressed: (1) How much physical activity do patients with
diabetes perform? (2) What are the perceived factors that prevent patients from doing more …

Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy

…, TM MacDonald, AD Morris, GP Leese - The Journal of …, 2010 - academic.oup.com
Context: For patients on T 4 replacement, the dose is guided by serum TSH concentrations,
but some patients request higher doses due to adverse symptoms. Objective: The aim of the …