RT Journal Article
SR Electronic
T1 Patients’ attitudes and perceptions towards treatment of hypothyroidism in general practice: an in-depth qualitative interview study
JF BJGP Open
JO Br J Gen Pract Open
FD Royal College of General Practitioners
SP BJGP-2017-0125
DO 10.3399/bjgpopen17X100977
A1 Rosie Dew
A1 Kathryn King
A1 Onyebuchi E Okosieme
A1 Simon Pearce
A1 Gemma Donovan
A1 Peter Taylor
A1 Graham Leese
A1 Janis Hickey
A1 Salman Razvi
A1 Colin Dayan
A1 Scott Wilkes
YR 2017
UL http://bjgpopen.org/content/early/2017/06/26/bjgpopen17X100977.abstract
AB Background Suboptimal thyroid hormone replacement is common in patients with hypothyroidism and the behavioural factors underlying this are poorly understood.Aim To explore the attitudes and perceptions of patients to thyroid hormone replacement therapy.Design & setting An in-depth qualitative interview study with patients with hypothyroidism residing in Northumberland, and Tyne and Wear, UK.Method Twenty-seven patients participated, of which 15 patients had thyroid stimulating hormone (TSH) levels within the reference range (0.4–4.0 mU/L) and 12 patients had TSH levels outside the reference range. A grounded theory approach was used to explore and develop emerging themes, which were mapped to the health belief model (HBM).Results Patients generally had a low understanding of their condition or of the consequences of suboptimal thyroid hormone replacement. Patients that had experienced hypothyroid symptoms at initial diagnosis had a better perception of disease susceptibility, and this was reflected in excellent adherence to levothyroxine in this group of patients. The main benefits of optimal thyroid replacement were improved wellbeing and performance. However, patients who remained unwell despite a normal serum TSH level felt that their normal result presented a barrier to further evaluation of their symptoms by their GP.Conclusion Educating patients with hypothyroidism regarding the consequences of inadequate thyroid hormone replacement may reduce barriers and improve treatment outcomes. An over-reliance on TSH as a sole marker of wellbeing reduced opportunities for clinicians to address patient symptoms. Evaluating symptoms in combination with biochemical indices, may lead to better patient outcomes than relying on laboratory tests alone.